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As such, complex I inhibitors like 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) or rotenone show preferential cytotoxicity to the DA neurons (Mizuno et al., 1987)

10.7150/thno.18219 Theranostics 228 JinY.OhK.OhS

The primary objective of this review is to elucidate the mechanisms by which adrenal hormone imbalance induces oxidative stress and investigate the potential contributions of nutritional antioxidants in mitigating such imbalances