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Nat Rev Drug Discov

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F.TazearslanC.MerkurjevD.OhgiK.MeluzziD.et al (2025)

As discussed in our paper, glutamine uptake inhibitors not only activate the function of Teff cells in the TME, but also up-regulate the expression of PD-L1 in tumor cells, which may inhibit the function of Teff cells