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Description

This single carbon metabolic process is mediated by enzymes such as methyltetrahydrofolate reductase (MTHFR), catechol-O-methyltransferase (COMT), and cystathione beta-synthase (CBS)

Secreted phosphoprotein 1 (SPP1)- and COL6A1-positive perivascular fibroblasts accumulated in enlarged perivascular spaces in the spinal cord of patients with sporadic ALS