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Reduce it and you risk defects

N Engl J Med 319:223226

Management tip: Prioritise B-vitamin-rich foods and supplements (especially B6, B12, and folate), reduce processed foods, manage stress, and have your homocysteine levels tested regularly

Sterol feedback regulation is characteristic of all genes involved in cholesterol biosynthesis and homeostasis, whereas cAMP-dependent regulation is unique, suggesting that CYP51A1 may play a tissue-specific role distinct from cholesterol biosynthesis