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Extracellular glutamate is efficiently taken up by the sodiumdependent excitatory amino acid transporters (EAAT) 1 and 2 (Todd and Hardingham 2020), while glycine uptake is mediated by the sodiumdependent transporters GlyT1 and GlyT2 (Marques et al

Glia 72 , 982998 (2024)

Our study explored how cancer-related resistance could be reversed by targeting BCAA metabolism, enhancing sensitivity to radiotherapy, chemotherapy, targeted therapy, and immunotherapy