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There are two main kinds of systemic sclerosis, according to the Scleroderma Foundation: Limited cutaneous scleroderma (formerly called CREST syndrome) The name CREST syndrome comes from symptoms that people with limited cutaneous scleroderma have: C alcinosis: Painful lumps of calcium in the skin that can happen on your fingers or other parts of your body R aynauds phenomenon: White or cold skin on the hands and feet when youre cold or stressed thats caused by blood flow problems E sophageal dysfunction: Problems swallowing and/or reflux caused by scarring in the esophagus S clerodactyly: Tightness and thickening of finger or toe skin that can make it hard to bend your fingers T elangiectasias: Red spots on the hands, palms, forearms, face, and lips caused by widened blood vessels CREST syndrome was used to describe limited cutaneous scleroderma before it was realized that patients also had internal organ involvement, says Virginia Steen, MD, Professor of Medicine at Georgetown University School of Medicine and the Chief of Division of Rheumatology