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De D, Jamal ME, Aydemir E, Khera A

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Usman et al., 2020), When B16F10 melanoma cells were treated with 050 m SP, it was found that SP to induce melanin synthesis in a dose-dependent manner by increasing the expression of MITF and tyrosinase via increasing CREB phosphorylation ( In vitro , SP at concentrations of 050 mol/L enhanced melanogenesis in vivo and in vitro by increasing melanin content and Tyr and MITF expression ( 7-Isopentenyloxycoumarin 7-isopentenoxycoumarin (Figure 6D), a natural pentenoxyumbelliferone derivative widely found in Rutaceae and umbelliferaceae, is a floral extract of Amaranthus retroflexus L., which is used as a food product in southern and central Italy (Preziuso et al., 2020)