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Development of antagonists that target FcRn, so as to increase IgG catabolism, thus represents a universal, yet targeted approach for the treatment of IgG-mediated autoimmune diseases [22]

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Discussion Given the potential of CTX as a therapeutic, it is of significant interest to understand the structural features important for function, as this information is likely to facilitate the development of CTX as a therapeutic

Hail N, Carter BZ, Konopleva M, Andreeff M