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However, more studies are needed to establish this role ( L732138) increases apoptosis in these cells (Zhang et al., 2000

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3 Inflammation and depression The relationship between inflammation and depression has received increasing attention because many studies show that the immune system plays a central role in how the body and brain respond to stress

In CKD, the damage to the kidneys prompts the nearby fibroblasts and pericytes to release inflammatory substances and initiate the development of the extracellular matrix (ECM) as a means of repairing the injury