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Figure 4 Elevated levels of proinflammatory cytokines (e.g., IL-1, IL-6, IL-23, IL-33, TNF, and IL-17) and reduced levels of anti-inflammatory cytokines (such as IL-10, IL-27, and TGF) are commonly termed cytokine dysregulation

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Notably, mitochondrial GSH (mGSH) constitutes a predominantly reduced pool, comprising 10-15% of the total GSH, with concentrations akin to the cytosol (10 to 14 mM) [8]