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Figure 1: Kaplan-Meier Curve for Overall Survival in KEYNOTE-189* *Based on the protocol-specified final OS analysis P+P+C = pemetrexed + pembrolizumab + platinum chemotherapy

CJC-1295 without DAC (also called Modified GRF 1-29) has a half-life of approximately 30 minutes, while CJC-1295 with DAC binds to serum albumin via a maleimide linker and extends the half-life to roughly 68 days, allowing weekly rather than daily dosing in research models