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Both mouse primary cortical neurons (10 or 20 M for 3 or 6 h) and a triple-transgenic AD mouse model treated with SF (56.4 or 282 mol/kg/day for 6 days/week for 8 weeks) exhibited enhanced brain-derived neurotropic factor (BDNF) expression, crucial for neuronal survival and synaptic plasticity, suggesting a potential epigenetic mechanism for SFs neuroprotective effects (61)

Surgical intervention, such as an anterior temporal lobectomy , can be curative when the epileptogenic focus is precisely localized using intracranial electrodes

Protein expression and purification N-terminally truncated (3-20) and C-terminally His-tagged CYP2E1 [33] was expressed in E

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