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By reinforcing the skins structural matrix, it effectively: Reduces the appearance of fine lines and deep wrinkles

PubMed: (peer-reviewed) Hosokawa R, et al

Statistical analysis was performed with Stat View 4.5 software (Abacus Corporation, Baltimore, USA) for Windows, the data were analyzed using one-way ANOVA followed by Fishers protected least significance difference [PLSD] post hoc test