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Activation of NRF2 reduces iron absorption, limits ROS production, and enhances cellular antioxidant capacity (87)

In a randomized controlled trial, 50 patients undergoing laparoscopic cholecystectomy were given either curcumin or a placebo, along with standard pain relievers to use as needed, upon hospital discharge

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However, the report describes the woman's symptoms as "idiosyncratic" and concedes they may have been caused by another ingredient in her supplement.33 Even if you feel that your risk of adverse events is low, we recommend speaking with your doctor before incorporating milk thistle (or any supplement) into your regimen