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With the continuous development of technology, the clinical efficacy and safety of VNS have been greatly improved

K.ManivasagamT.et al (2013)

NF-B is also a key factor in regulating NADPH oxidase expression and it is possible that there is a positive feedback loop in which NF-B activation by oxidative stress leads to further radical production via NADPH oxidase (Nikolova et al., 2005

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