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Improvements in disease status in these instances may cause a reduction in INR and necessitate an increase in warfarin dose

severe infections or sepsis, irregular blood vessel surface (vasculitis, artificial heart valve), or, rarely, disseminated intravascular coagulation or DIC (a serious complication of overwhelming infections, traumas, burns, or pregnancy)

Immunoaffinity chromatography Utilizes antibodies to purify peptides, viruses, hormones, and enzymes

Signs of Major Bleeding While on a Blood Thinner Blood in urine, turning it a pink, red, or Coca-Cola brown color Blood in stool, making it either bright red or black and sticky (tarry) Coughing up red or brown-tinged sputum Vomiting up anything that looks like coffee grinds (always alarming!) Its always useful to have The Chat with new blood thinner patients