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We used deuterium magnetic resonance spectroscopy (DMRS) to provide quantitative information about metabolic flux, fluorodeoxyglucose positron emission tomography (FDG-PET) to measure brain glucose metabolism, and resting state-functional MRI (rs-fMRI) to measure brain functional connectivity

Women suffer from a three-fold increased risk for migraine symptoms compared to men 67

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However, there are subtle differences among the agents in terms of receptor selectivity (-, 1 -, and 2 -adrenergic receptors), lipid solubility, membrane-stabilizing activity, and potassium channel blockade that result in varied clinical manifestations