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As ferroptosis is driven by lipid peroxidation and oxidative stress, xCT sustains glioblastoma survival by maintaining intracellular cysteine levels, which serve as a precursor for GSH synthesis, a key antioxidant that mitigates ROS-induced lipid peroxidation [49,50,51]

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Lipo C's amino acid components (methionine, inositol, choline) perform optimally when dosed 23 hours before sleep, positioning peak plasma concentration to coincide with nocturnal growth hormone release and lipolysis