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Another recommends 500mcg

It is often used in fat burning and weight management supplements, and is also used in potential metabolic and anti-aging research

But heres what we do know: Some people experience gastrointestinal side effects on tirzepatide, such as nausea, vomiting, diarrhea, or constipation Vitamin B12 supplementation is generally considered safe, but high doses might cause headache, nausea, or bowel changes Side effects for both usually improve with time as the body adjusts If youre curious about taking tirzepatide and B12 together or if you are unsure whether you may have nutritional deficiencies, talk to your provider before making any changes

Vitamin B12 helps maintain a healthy digestive system, it also protects against heart disease by curbing and improving unhealthy cholesterol levels, protecting against stroke and high blood pressure