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Description

Melatonin increases the expression of cadherins (E-cadherin) by preventing the interaction of NF- with the junctional enhancer protein CCAAT (C-EBP), integrins (1-integrin) by reducing the expression of v3 integrin, occludin (tight junctions) [28,29] and vimentin, proteins involved in cell adhesion, migration, and invasiveness

Petrukhin et al., 1993

Since flavonoids can halt cell cycles of cancer cells via several mechanisms, flavonoids are potential candidates for efficient anticancer therapy, or as pharmaceuticals able to overcome resistance to chemotherapy (Luo et al