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However, some of these conclusions and other indications for pediatric use of corticosteroid, e.g., severe asthma and wheezing, are based on adequate and well-controlled trials conducted in adults, on the premises that the course of the diseases and their pathophysiology are considered to be substantially similar in both populations

It is important to note that baclofen does not have the same impact on the brain regions involved in anxiety or sedation, which distinguishes it from benzodiazepines

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J Comp Neurol 212:3852 Mesulam M-M, Mufson EJ, Levey AI et al (1983) Cholinergic innervation of cortex by the basal forebrain: cytochemistry and cortical connections of the septal area, diagonal band nuclei, nucleus basalis (Substantia innominata), and hypothalamus in the rhesus monkey