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5.3 S-acylation in -cells S-acylation has been shown to be an important regulator of ion channels, vesicle trafficking, and small GTPAses, controlling many aspects of protein sorting, membrane localization, and lipid metabolism ( ATP channel activity is strongly modulated by S-acylation, which causes channel opening, counteracting the ability of ATP to close the channel ( 2+ channels ( 2+ influx and insulin exocytosis ( Figure 2 )

10.1016/j.biopha.2022.113941 111 LouT.JiangW.XuD.ChenT.FuY

Therefore, further in-depth research should be performed to determine whether cysteine contributes to metabolic dysfunction related to breast cancer

In support of this notion, indirect calorimetry revealed an increase in the respiratory exchange ratio (RER) of p53 KO mice during the refeeding phase (Fig