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Enhancer remodeling during adaptive bypass to MEK inhibition is attenuated by pharmacologic targeting of the P-TEFb complex

Second, the cross-sectional nature of the study limits our ability to establish causality and exclude the potential reverse causation between biomarkers and diseases, highlighting the need for larger interventional studies

In this randomized, comparative trial, 90 patients with ME/CFS were given either 2 grams per day of Acetyl-L-Carnitine (ALCAR), 2 grams per day of Propionyl-L-Carnitine (PLCAR), or a combination of both over a 24-week period