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The major drawback to using VLP as a drug delivery strategy is that, because of its viral proteinaceous particle and easy uptake by dendritic cells, it triggers an innate immune response (145)

76: 20610 Miyajima A, Nakashima J, Tachibana M, et al

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(6) Such findings might reflect an increase in somatotroph cell populationsthe specialized pituitary cells primarily associated with synthesizing and releasing growth hormone