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Advancing gene therapy for phenylketonuria: from precision editing to clinical translation

The mice were anesthetized with 4% chloral hydrate and maintained their body temperature at 37 C

4 and Supplementary Table 2 for more details on these two methods and the gene lists

Figure 1 A major conceptual advance in lactate biology was the discovery of protein lactylation, a novel post-translational modification directly derived from lactate metabolism (Vander Heiden et al., 2009)