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However, whether the addition of Zn 2+ would affect the angiogenic ability of Cu 2+ -Qu complex was a key issue to be clarified in this study, since the Zn 2+ alone is not considered as an activator of angiogenesis [80]

Mechanisms of Collagen Synthesis The collagen synthesis mechanisms involve several key pathways: MAPK/ERK Pathway Activation This pathway upregulates collagen gene expression and promotes fibroblast proliferation, creating the cellular foundation for tissue repair