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Clinical signs are indistinct and include lethargy, depression, ataxia, anorexia and intermittent vomiting, and in severe cases, can induce neurological disease and blindness in cats

Standard oral glutathione has very low bioavailability a term that refers to how much of a substance actually enters the bloodstream to be used

Additionally, TSA can induce the expression of the major ING1 isoform p33, a type II tumor suppressor involved in histone modification and DNA damage response, and ING1 has been shown to participate in glioma-induced angiogenesis, serving as a cross-node that links acetylation-regulated angiogenesis to apoptosis through the FADD/caspase 3 signaling pathway (Tamannai et al., 2010)

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