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Another important molecule within the antioxidant network, necessary for the reconversion of ascorbate into DHA, is glutathione

Spermatozoa are particularly vulnerable to OS as they lack the necessary cytoplasmic-antioxidant repair systems and their membrane is rich in polyunsaturated fatty acids which render them susceptible to OS-induced LPO

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Moreover, recent studies have confirmed the protective role of QR against oxidative damage during the freeze-thaw procedure, as QR-supplemented freezing extender induced significant quality improvement in buck [136], bull [137], dog [138], human [139], and stallion [140] sperm