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When odours derive from female donors, this activation is more evident in female than male receivers, while male odours elicit similar activation in male and female receivers

In a study by Yang [135], cGAMP treatment resulted in a 6.4-fold increase in intratumoral CD8 T cells, a 40% reduction in CD31 vascular density, a 1.7-fold increase in NG2 pericyte coverage, and a 1.5-fold increase in COL4 basement membrane coverage (Fig