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A reticulocyte count may also be checked, as a rise in reticulocytes (young red blood cells) within the first week indicates effective bone marrow response

[DOI] [PubMed] [Google Scholar] 89.Li Y, Qi X, Li H, et al

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Couture Med Spa reports a similar pattern among its own tirzepatide and semaglutide patients, listing mild nausea or upset stomach, temporary irritation at the injection site, fatigue or headaches, and changes in appetite, and adds that most side effects fade as the body adjusts to treatment (couturemedspa.com)