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To investigate whether DAM and DAA are associated with neurodegeneration in GCLC-KO mice, we conducted qRT-PCR analyses of DAM and DAA-related genes using cortical samples from 4-month-old GCLC-KO and WT mice (Fig

Microglia embedded in neural organoids with a forebrain identity were chosen as a model as the HIV-1 JR-CSF strain is a viral isolate that preferentially infects microglia and perivascular macrophages in the CNS